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The effects of a B12 injection can be felt within a few hours to a few days, depending on individual metabolism and deficiency levels

Compare that to tirzepatide weight loss timelines showing average losses of 20 to 22 percent of body weight (often 40 to 50 pounds or more) over 12 to 18 months

These drugs also degrade quickly unless kept under specific temperature conditions, making delivery through a patch even more impractical