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Side Effect Mitigation: A low starting dose helps to prevent or lessen the severity of common gastrointestinal side effects
When the medication becomes less potent, it may deliver a lower dose than intended, making treatment less effective
However, rushing the process or cutting corners can be dangerous
As a result, these bonds weaken considerably under the influence of charge transfers of up to 1 electron, leading to their breaking during CASSCF geometry optimization
Mochiki E, Suzuki H, Takenoshita S et al (1998) Mechanism of inhibitory effect of glucagon on gastrointestinal motility and cause of side effects of glucagon
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