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In addition to pancreatic beta cells that secrete insulin, pancreatic alpha cells secrete glucagon in the pancreas
GLP-1 injections are generally considered safe for weight loss when used under the supervision of a healthcare provider
Both classes of agents reduce cardiometabolic risk factors such as HbA1c, body weight, blood pressure and albuminuria, although the effects of GLP-1 receptor agonists on glycemia and body weight are substantially greater than those of SGLT2 inhibitors
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