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Clinical trials are investigating metformin as an anti-cancer therapy in breast, prostate, endometrial, and pancreatic cancers (Dowling 2011)

Indeed, it is well documented that regular consumption of high-glycemic index meals, compared to isoenergetic meals with the same carbohydrate content, results in higher average 24-h blood glucose and insulin levels, higher C-peptide U-excretion, and higher HgbA1c in both non-diabetic and diabetic individuals [26, 27]