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Identification of brain neurons expressing the dopamine D4 receptor gene using BAC transgenic mice
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This low-dose approach turns the drug into a manageable background aid rather than a dominant physiological force
rAAV lacks virally encoded genes, and therefore can be used to infect adult tissue without rendering an immune response
These include a body mass index (BMI) of 35 kg/m or above (or 32.5 kg/m or above for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds) with at least one weight-related comorbidity, and previous unsuccessful attempts at weight loss through diet and exercise
