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These medications should be avoided by people who are pregnant or breastfeeding, those with a history of pancreatitis, and anyone with a personal or family history of medullary thyroid cancer or MEN2 syndrome

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Comparative exercise models and combination trials with other antioxidants (e.g., vitamins C and E) are also recommended to broaden applicability and mechanistic insights

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A series of longer clinical trials provide a better idea of how much weight people lose throughout treatment