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GPX8 can inhibit the oxidative stress response of hepatocellular carcinoma cells ( A great deal of research on the structure and function of GPX in mammals has helped us understand the essential functions of this class of proteins

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Renal OCTN2 expression and activity increase when the carnitine concentration is reduced in the plasma and/or glomerular filtrate, whereas OCTN2 mRNA expression levels remain unchanged in the gut, liver, or skeletal muscle [254], highlighting the central role of the kidney in maintaining carnitine homeostasis

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