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Research on mice revealed a 7% reduction in body mass within just 10 days without impacting appetite
Notoginsenoside R1 activates the NAMPT-NAD(+)-SIRT1 cascade to promote postischemic angiogenesis by modulating Notch signaling
It is studied for effects on glucose metabolism, mitochondrial efficiency, and NAD+-dependent pathways
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By influencing S-adenosylmethionine (SAM) levels, it also plays a role in epigenetic regulation and longevity-related gene expression, linking energy metabolism with cellular lifespan
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