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Through coordinated GLP-1R and GIPR activation, tirzepatide enhances glucose-dependent insulin secretion, improves glycemic control, contributes to lipid homeostasis, and reduces appetite and food intake, supporting its clinical use in obesity and type 2 diabetes [13]

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Retatrutide, a newer triple agonist targeting GIP, GLP-1, and glucagon receptors, has a half-life of approximately six days

Ten units on an insulin syringe equals 0.1 mL of liquid

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