"With anything medical, whether we're talking about a vaccine or antibiotics, there's always side effects," she explained, listing the potential downsides
They are now part of a broader medical discussion about obesity, insulin resistance, cardiovascular risk, fatty liver disease, inflammation, body composition, appetite signaling, and long-term metabolic health
And its anabolic-related genes include fibroblast growth factor-21 (FGF21), SREBP-1c, fatty acid synthase (FAS), acetyl-CoA carboxylase (ACC-a), liver X receptor (LXR), suppressor of cytokine signaling-3 (SOCS-3), etc
Chatterjee, Nutrients 5, 525 (2013) , E.V
While both medications have shown great promise, tirzepatides dual action on both GLP-1 and GIP might give it the edge in terms of overall efficacy, particularly when it comes to weight loss