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Supplemental Fig
Taurine deoxycholic acid (TUDCA), loganin, and CXCL2 blocking therapy all have the effect of modulating NLRP3, and all three have also been shown to improve SCs mortality in the HG environment (58, 109, 110)
Some studies suggest that using semaglutide and topiramate together may lead to better weight loss outcomes compared to using either drug alone
Ozempic is a GLP-1 receptor agonist that helps improve glycemic control by stimulating insulin secretion, inhibiting glucagon release, and slowing gastric emptying
Normalization of glucose levels and sharp reduction in body weight caused by semaglutide has just been found to reduce the incidence of cardiovascular events, even in people without diabetes
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