Animal studies have reported outcomes including reduced adiposity, improved insulin sensitivity, and altered lipid profiles, all without changes in food intake
You also need to be ready to make some lifestyle modifications long term for your results to be sustainable
However, only the animals that were administered with the incretin-based compounds (GLP-1 and GLP-1MK-801) displayed increased baseline-corrected glucose-stimulated insulin secretion (Extended Data Fig
"The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms." In the UK, the most commonly used GLP-1 therapies are Novo Nordisk's semaglutide-based Ozempic for diabetes and Wegovy for obesity, as well as Eli Lilly's Mounjaro (tirzepatide), which are all given as weekly injections
Questions to ask your doctor Given my health history, is a GLP-1 medication appropriate for me at all