December 2025 brought FDA approval for the oral version, designed for adults with obesity or overweight who also have at least one connected health issue
Biotin with an important caveat Biotin, also known as vitamin B7, supports keratin production and is widely marketed as a hair health supplement
B12, folate, iron, and zinc are particularly important for oral mucosal health, and deficiency in any of these can manifest as recurrent mouth ulcers, glossitis (tongue inflammation), or angular cheilitis (cracks at the corners of the mouth)
Under normal conditions, it exists in a benign, non-invasive budding yeast form, held in check by competing beneficial bacteria (predominantly Lactobacillus and Bifidobacterium species), a functional gut immune barrier, and adequate nutritional status
What monitoring is recommended for patients taking oral semaglutide in a primary care or internal medicine setting