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GLP-1 has been tested as a regulator of anxiety behavior and both GLP-1 and exendin-4 (administered ip , into the lateral ventricle or intra-dorsal raphe) induced anxiety-like behavior, which was measured in the black and white box, elevated plus maze and open field tests in Spraque-Dawley rats [86]

Menopause: Menopause can lead to changes in body composition and fluid distribution due to hormonal shifts, impacting electrolyte balance

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Acute kidney injury : Severe vomiting or diarrhoea can lead to dehydration and kidney problems

29 On another note, both pooled and Kaplan-Meier analyses did not reveal any significant relations between mortality and the extent of tumor resection, which begs the question of whether adjuvant chemotherapy may be of help in improving the overall survival associated with this aggressive tumor