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Summary And Next Steps Chronic cold legs have many potential causes: vascular disease, neuropathy, metabolic issues, Raynaud's, musculoskeletal factors, and environmental contributors, most commonly

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If symptoms creep back, revert to your previous B12 injection schedule

The effects are not as good as oral supplementation, & we do not routinely add this to your melasma or skin lightening program

View all FAQs Important safety information and common side effects The most commonly reported side effect is irritation of the area where the injection is administered. If this occurs, consider changing placement on the body or use injections less often