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We have a broader overview of weight loss medications if you want the longer landscape view
Baig MMA, Irfan SA, Sumbal A, Sumbal R, Kumar S, Ahmad J, et al
GLP-1 is both influenced by and exerts effects on variables like the microbiome, eating behaviour, glucose tolerance, metabolic profile, medication, sex and weight
They slow digestion further and dramatically increase nausea risk
Its a small trial with only 1-year follow up and lacking hard endpoints such as hospitalization or cardiovascular deaths, but the results for symptomatic relief and gain in physical activity are certainly very encouraging
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