B Vitamins (especially B6, B12, and folate): Support the methylation cycle, which plays a key role in detox and glutathione recycling
The use of the highly selective and strong mGluR5 receptor antagonist (3-[2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine (MPEP) reduced reference and working memory in a radial arm maze task in rats [31]
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Research consistently shows an inverse association between serum B12 and serum MMA levels, although researchers havent found specific cutoff points for determining B12 deficiency by way of serum B12 or MMA levels using cross-sectional data (Bailey, 2011, Bailey, 2013)