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It is most potent at the GIP receptor (EC50 of 0.0643 nM), moderately potent at GLP-1 (EC50 of 0.775 nM), and least potent at the glucagon receptor (EC50 of 5.79 nM)

She added that the consistency of the decreased likelihood of dementia diagnosis across the different medications was particularly noteworthy. Past studies have reported associations between GLP-1 receptor agonists and dementia, with some suggesting a reduced dementia risk after starting the medication and others indicating variability depending on how these medications cross the blood-brain barrier, Bartlet and colleagues wrote

If you are curious about how GLP-1s impact women in particular, you can dive deeper on our sex-specific guide, to see unique considerations

If physician-approved, using a reputable pharmacy and following strict storage and handling protocols is essential

The bacteriostatic water guide covers the proper ratios and techniques