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Semaglutide, an FDA-approved once-weekly injection, has been proven to help people lose weight and maintain it
doi:10.1001/jama.2021.3004 Marso SP, Bain SC, Consoli A, et al
[1] Additionally, GLP-1 receptor agonists slow gastric emptying and promote satiety through central nervous system pathways, contributing to weight reduction in many patients
Large meta-analyses involving over 4,000 stool samples from North America, Europe, and Asia show that PD is associated with a reproducible pattern of gut dysbiosis characterized by SCFA-producing genera depletion, opportunistic pathobiont enrichment, and consistent shifts in functional pathway gene expression [187]
