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if your eGFR falls below 45 mL/min/1.73m, metformin typically must be reduced or discontinued to prevent lactic acidosis risk

[20] [21] Your healthcare provider will also investigate potential causes of iron deficiency, which may include: Dietary inadequacy (particularly relevant with significant appetite suppression) Gastrointestinal blood loss (requiring investigation if no obvious cause) Menstrual blood loss in premenopausal women Malabsorption disorders such as coeliac disease Chronic inflammation or other underlying conditions NICE guidance (NG12) recommends urgent suspected cancer referral (two-week wait) for adults aged 60 and over with iron deficiency anaemia

Should Chronic Pain Be Managed Differently During Treatment Yes

Distributing protein intake across meals helps maintain a steady supply of amino acids for hair follicle function

However, this review highlights the heterogeneity in patient responses, indicating that some patients exhibit resistance to DAs and may benefit from surgical resection as a first-line treatment, as summarized in Fig