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Vitamin B12 is not a substitute for folic acid and since it might improve folic acid deficient megaloblastic anemia, indiscriminate use of vitamin B12 could mask the true diagnosis

Nagata, S., et al

While tirzepatide is already available on prescription in the UK, retatrutide is still in clinical trials

B12 deficiency produces a recognizable cluster of symptoms: fatigue, weakness, neurological changes including tingling or numbness in the extremities, cognitive fog, and in more severe cases, megaloblastic anemia

Patients may have an enhanced response to vaccines and fewer symptoms of chronic infections
