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A peptide is not a plan
Limited proteolysis was performed by enzymatic digestion at 37 C adding bovine trypsin (Sigma-Aldrich, Italy) or proteinase K (Sigma-Aldrich, Italy) to protein extract at a ratio 1:100 enzyme/substrate (w/w)
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The ability of AMG 133 to lower body weight and improve metabolic markers in male obese mice and cynomolgus monkeys is reported by researchers, who also confirm the GIP receptor antagonist and GLP- 1 receptor agonist activities in cell-based systems
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