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Active lignans isolated from schisandra, particularly schisandrin A, appeared to reverse P-glycoprotein-mediated multidrug resistance of various cancer cell lines to doxorubicin, vincristine, and paclitaxel (20)
Recommendations of the Polish Society of Endocrinology and the Polish Society of Paediatric Endocrinology and Diabetology
The current understanding is that DSIP is a sleep normalizer rather than a simple sleep inducerit restores disrupted sleep architecture, increasing slow-wave sleep in insomniacs while having minimal effect on normal sleepers
For example, in 2% albumin condition, the IC 50 is 5.39 when lipidation occurs at position 27, yet at position 26 it reaches 357
Chen HM, Wei W, Smith D, Chan SC
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