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Timing depends on the nutrient: fat-soluble compounds and CoQ10 are best taken with a meal containing fat, while collagen peptides and oral hyaluronic acid can be taken any time daily for consistency-many prefer morning with coffee or evening with a snack

Particular caution is needed when taking bisacodyl alongside diuretics, corticosteroids or digoxin, as the resulting hypokalaemia may increase the risk of digoxin toxicity

doi:10.1074/jbc.M802030200

References Liu, C