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Limitations & Unknowns While promising, there remain many uncertainties: Causality not yet proven : Many studies are associative
Neither study showed a significant increase in amylase (7% for both studies) or lipase (28% in the LEADER trial and 31% in the SCALE trial) values after starting liraglutide compared with placebo, and the positive predictive values of amylase and lipase for pancreatitis were less than 1%
It offers a non-injectable option for individuals looking to manage their weight
Mitophagy defects have been found in neurodegenerative diseases such as Hungtingtons disease, Alzheimers disease and Parkinsons disease (Schapira and Gegg, 2011
10.1089/thy.2006.16.455 19 Fontagn DicharryS.GodinS.LiuH.Antony Jesu PrabhuP.BouyssireB.BuenoM.et al (2015)
