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Topiramate is an anticonvulsant that works by blocking sodium channels, enhancing GABA-A activity, and antagonising glutamate receptors mechanisms unrelated to weight management
Many patients using semaglutide for weight loss worry about losing muscle along with fata concern backed by research showing that rapid weight loss can reduce lean body mass by 2030% without proper resistance training and nutrition
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Short term suitability likely depends on mechanism and safety data
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