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There may have been other things in the mix such as Iron etc, but its highly unlikely there's a B6 toxicity issue

Zero effect on my appetite

SURPASS-2 showed tirzepatide was superior to semaglutide 1mg for both A1C reduction (2.09% vs 1.86%) and weight loss (12.4% vs 6.2%) at the 15mg dose, establishing the clinical relevance of dual-agonism over selective GLP-1 agonism

The injections are relatively painless, with most patients experiencing only a slight pinch at the injection site

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