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FIGURE 2 3.2 GHK-Cu inhibited the expression of inflammatory cytokines in DSS-induced colitis mice Figures 3AD show that Western blot analysis detected marked elevations in IL-1, IL-6, and TNF- levels in colonic tissue of DSS-induced colitis mice, indicating a robust inflammatory response
10.1074/jbc.M208704200 J
In addition, 50 M DPA significantly reduced BV2 cell viability after stimulation with 100 ng/mL LPS, demonstrating that n-3 DPA may inhibit microglia-NF-B and MAPK p38 by balancing microglia M1 and M2 polarization (70)
Most side effects are dose-dependent, meaning lower doses produce fewer issues
A rigorous study found that G-CSF use is associated with lower all-cause mortality in patients receiving chemotherapy, especially in those on intensive dosing schedules (Lyman 2013)
