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Changing the dosing regimen or the form of iron supplement may reduce gastrointestinal side effects, for example: Intermittent, high-dose iron supplementation (one, two, or three times a week on non-consecutive days) may be a feasible alternative to daily supplementation among pregnant women who are not anemic and have adequate antenatal care

Papagiannakopoulos for providing KP mouse cell lines (HY15549, Tom2)

Report persistent, worsening or concerning reactions promptly

Store the sealed lyophilized vial at -20C, protected from light, with a 24-month shelf life from manufacture

While gastrointestinal AEs such as nausea and vomiting dominate safety reports 8 and recent pharmacovigilance studies highlight increasingly recognized risks including acute pancreatitis, nephritis, hypotension, and syncope 9,10,11 , emerging data suggest that GLP-1 RAs may be associated with neurological adverse events (NAEs) 12,13