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Statin-induced myotoxicity (SIM) is one of the most common adverse effects, prevalent across all ages, genders, and ethnicities

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It is an engineered form of naturally occurring HGF fragment NK1, which has the advantages of better stability and is easier to be produced and might be used as a therapeutic medicine for acute and chronic liver disease (Ross et al., 2012)

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As expected, when increasing the incubation time with GSH, UPFB displayed a time-dependent GSH consumption capacity (Figure 7E)

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The influence of MAT1Aon the mitochondrial function is largely mediated by its direct methylation regulation on CYP2E1 (64)

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