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In OA-mimicking inflammatory conditions, the platform scavenged ROS and released oxygen, downregulated MMP-13, IL-1, and TNF-, and, in monoiodoacetate-induced rat OA, delayed cartilage degeneration while decreasing pro-inflammatory cytokines and increasing anti-inflammatory mediators (Peng et al., 2025) (Figure 1D)

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Clinical study FY25_DRA.36, Data on file

Exercise also reduced systolic and diastolic blood pressure and led to decreased BMI in those who undertook more than six months of exercise