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Nov 30 2020;12(12)doi:10.3390/nu12123691

Both PTI and ETI are involved in overlapping downstream immune responses, including activation of mitogen-activated protein kinases (MAPKs), calcium-mediated signaling, reactive oxygen species (ROS) burst, transcriptional reprograming, callose deposition, and biosynthesis of salicylic acid (SA) 2,3

It requires a good-faith medical exam by an authorized prescriber, appropriate documentation, and informed consent that presents benefits and risks honestly rather than in an alarmist or oversold way

Internationally, IV NAD+ is offered through licensed clinics in many jurisdictions

These are fundamentally different approaches to blood sugar management, with different side effect profiles, different effects on body weight, and different implications for long-term health