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The N-terminal extracellular domain (ECD) of GLP-1R is important for GLP-1 binding and the crystal structure of the GLP-1/ECD complex was reported previously
Cell lysate was then diluted with lysate buffer and divided into two aliquotsone treated with C1-27 (100 M) and the other treated with 1% DMSO
10.3390/healthcare13030300 52
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Int J Mol Sci 20:3328 Kelly J, Kennedy P, Cryan J, Dinan T, Clarke G, Hyland N (2015) Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders
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