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Nrf2 is involved in not only the regulation of GSH synthesis and reduction via upgrading some enzymes and proteins (SLC7A11, GCLM, GCLC, GR) but also the activation of GSH-dependent antioxidant enzymes (GPX, GST) [200, 201]
The body uses glutathione to convert toxins into a compound that is water-soluble, allowing them to be excreted through the urine or bile
She was referred for further evaluation of her chest pain, which, in the context of her family history of early-onset heart attacks and her morbid obesity, understandably concerned her primary care doctor
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For diabetic patients, this poses a substantial threat, as corticosteroids are known to induce hyperglycemia [34]
