Key elements of the study design include data-independent acquisition (DIA)-proteomics analysis performed on synchronized ring-and trophozoite-stages of artemisinin resistant and sensitive parasites to evaluate differential protein expression, with a focus on PfK13 protein levels
Gameiro PA, Yang J, Metelo AM, Prez-Carro R, Baker R, Wang Z, Arreola A, Rathmell WK, Olumi A, Lpez-Larrubia P, Stephanopoulos G, Iliopoulos O
Detection and application of 5-formylcytosine and 5-formyluracil in DNA
Liver injury in NAFLD is caused by two mechanisms in general: (1) by peripheral resistance to insulin, and (2) by intrahepatic oxidative stress, whether with an increase of reactive oxygen species and reactive nitrogen species (ROS and RNS) and/or as a result of the decrease in antioxidant tissue levels
BMC Pharmacol