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Lower scores are better , thus the authors considered this data as potential evidence supporting slowing of disease progression

Important observations All five clinical trials that were included in the analysis reported GLP-1 receptor agonist-mediated reduction in substance use disorder, with two trials respectively reporting a significant therapeutic impact of GLP-1 receptor agonist in reducing alcohol use disorder and nicotine use disorder

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However, the lack of a placebo control group limits interpretation, as placebo responses in eating disorder trials can be substantial