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He is concerned that people who view exercise only as a weight-loss strategy might be less inclined to be physically active after taking one of the new GLP-1 drugs by thinking, Why exercise since I can lose weight with a drug? That would be a big mistake.
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It is widely recognised that metformin improves glycaemic control with a good safety profile, weight neutrality or weight loss, lack of associated hypoglycaemia, reduced cardiovascular mortality and low cost [3]