The key modifiable risk factors for cardiovascular disease include: high blood pressure elevated LDL cholesterol high triglycerides, insulin resistance, smoking excess visceral adiposity physical inactivity chronic stress poor sleep alcohol use and diet quality Most of these can be influenced by nutrition and lifestyle, meaning that the everyday choices men make have a significant and compounding effect on their long-term cardiovascular risk
Early animal studies suggest possible roles in wound healing and gut protection
Possible side effects include injection-site soreness, redness, nausea, or headache
However, despite affinity, albeit lower, of tirzepatide for the GLP-1 receptor, tirzepatide had no effect on body weight, food intake, fasting insulin, endogenous glucose production and insulin-stimulated glucose uptake in skeletal muscle and subcutaneous white adipose tissue of GLP-1 receptor knockout mice [89]
For most people with adequate subcutaneous fat, 90 degrees works well