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I think that stigma creates problems, for both patients and clinicians.

Hypoglycemia : For patients with diabetes, particularly those also taking insulin or sulfonylureas, hypoglycemia (low blood sugar) is a risk

Native Americans were chewing on the bark of the white willow for pain relief and fever reduction long before the barks salicin led to the invention (and, later, FDA approval) of aspirin

The study concluded that GLP-1 RAs did not trigger new clinical SLE manifestations above expected background rates while producing significant weight loss benefits

Paired-end sequencing of the library was performed using the Illumina HiSeq platform (Illumina Inc., San Diego, CA, USA)