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However, there are some important organ-specific effects to know about: Gastrointestinal effects increased bowel movements, red stool color

However, this IF-mediated pathway is saturable, with absorption plateauing at about 1.52 micrograms per dose

But only a subset develop liver injury

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As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively