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National Center for Complementary and Integrative Health notes that randomized, placebo-controlled trials are the gold standard because they help determine whether apparent improvement is due to the treatment or to chance
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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