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Additionally, these agents suppress glucagon secretion from pancreatic alpha cells, slow gastric emptying, and promote satiety through central nervous system pathways, leading to reduced food intake and weight loss
For example, some patients are struggling with weight loss due to nutritional imbalances or skipped meals
Endocrinology 158(12):41394151 Noria SF et al (2023) Weight regain after bariatric surgery: scope of the problem, causes, prevention, and treatment
Some patients carry genetic variants in the FTO and MC4R genes that affect appetite regulation and alcohol metabolism simultaneously
Step-Up Dosing To Minimize Side Effects The recommended Wegovy dosing schedule uses a step-up approach to improve tolerance
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