Those with a BMI greater than 25, with an increased weight related risk or diagnosed with a weight related medical condition, may also benefit
When those junctions are compromised, by NSAIDs, alcohol, chronic stress, or repeated antibiotic courses, the result is a low-grade inflammatory state that shows up as bloating, systemic fatigue, food sensitivities, and immune dysregulation
Species can differ substantially in absorption, transport, hepatic metabolism, renal handling and off-target effects
In adipose tissue, inhibition of NNMT suppresses de novo lipogenesis, normalizes fat content, and improves insulin sensitivity 2-3
Collagen and Extracellular Matrix Support: Collagen is a vital structural protein in tendons, ligaments, and joints