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These medicines mimic the action of naturally occurring GLP-1, a hormone produced in the intestine that plays a crucial role in regulating blood glucose levels and appetite

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MR helps mitigate confounding biases by leveraging the random allocation of genetic variants at conception and exclude reverse causation, as genetic determinants precede disease onset [26]

Oxidative stress and ROS formation are markedly increased by uncontrolled hyperglycemia (2,6)