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The slides were stained using multiplex IHC (mIHC) according to methods similar to the mIHC described for human islets (55)
The prevalence of metabolic dysfunction in autoimmune disease may relate to chronic inflammation, corticosteroid therapy, reduced physical activity due to disease burden, or shared genetic susceptibilities
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These meds trick the body into thinking that it has more of the hormone than it actually does, which leads to increased amounts of insulin (which helps with insulin resistance)
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