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These model values correspond well to the values in the literature

Naturally derived heme-oxygenase 1 inducers and their therapeutic application to immune-mediated diseases

Alterations in G6PD levels may promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in a human melanoma xenograft model, and G6PD regulated STAT3 activity via the NADPH oxidase 4-NADPH-ROS-proto-oncogene tyrosine protein kinase/protein-tyrosine phosphatase 1D signaling pathway in A375 melanoma cells (69,70)

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And higher doses have also occasionally been linked to eye issues that do not occur at lower levels