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studies suggest it does not significantly impact prolactin, cortisol, or ACTH levels, making it a preferred subject for clean signaling research
References Schett G, McInnes IB, Neurath MF
Members of the Rho GTPase family (e.g., Rac1, Rac2, Rac3, and cdc42) have been implicated in their activation by binding to an alternate site on the N-terminal PH domain followed by subsequent recruitment to the plasma membrane
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