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Considering the mechanistic overlap in the development and progression of CKD in type 1 and type 2 diabetes, there exists a strong rationale for simultaneously developing novel CKD therapies for use in both type 1 diabetes and type 2 diabetes and studying the repurposing of existing type 2 diabetes CKD therapies for the treatment of CKD in people with type 1 diabetes

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Supernatants were removed, diluted 1:1 with 2% acetonitrile in 0.1% formic acid (water), filtered, and analyzed by HPLC-MS/MS

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