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roughly 50-98 % of an administered dose is renally excreted unmetabolized, underscoring the low intrinsic toxicity

Adverse Reactions / Side Effects Nausea Diarrhea Decreased appetite Vomiting Constipation Dyspepsia (indigestion) Abdominal pain If side effects are severe or persistent, contact your healthcare provider

Analytical Cell Pathol (2021) 2021

In male rats experiencing transient ischemic stroke, UA treatment induced IL-6 expression, upregulated STAT3 and NF-B p65 phosphorylation, induced Socs3 expression, and maintained the ramified morphology of Iba-1-positive microglia in the cerebral cortex, suggesting an anti-inflammatory effect of UA [54]