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In diabetic mice, rescuing PINK1-mediated mitophagy by caffeic acid phenethyl ester could protect TECs against ferroptosis (79, 200)
For example, the compound ferroptocide was recently identified as a potent ferroptosis agonist that covalently binds to thioredoxin (TXN), a 12-kDa ubiquitous oxidoreductase in the thioredoxin antioxidant system [110]
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